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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes.

PURPOSE: To report a case of rofecoxib (Vioxx)-associated Stevens-Johnson syndrome with corneal and conjunctival changes. DESIGN: Interventional case report. METHODS: Case report of a 62-year-old woman with systemic lupus erythematosus ( SLE) taking rofecoxib for arthritis for 3 weeks. RESULTS: Stevens-Johnson syndrome after 3 weeks of rofecoxib therapy. CONCLUSION: This case report suggests that oral rofecoxib may trigger Stevens-Johnson syndrome, potentially causing symblepharons, corneal neovascularization and cicatricial ectropions.[1]

References

  1. A case of rofecoxib-associated stevens-johnson syndrome with corneal and conjunctival changes. Goldberg, D., Panigrahi, D., Barazi, M., Abelson, M., Butrus, S. Cornea (2004) [Pubmed]
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