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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Growth factor receptor expression in orbital lymphangioma: possible therapeutic implications.

OBJECTIVE: To examine the expression of molecules targeted by imatinib mesylate (STI571;Gleevec) and epidermal growth factor receptor (EGFR) inhibitors in orbital lymphangiomas. DESIGN: Retrospective observational case series. PARTICIPANTS: Six patients with orbital lymphangioma treated at four institutions between March 2000 and December 2002. METHODS: Tissue specimens and medical records from six patients were collected. Immunohistochemical analysis was performed using antibodies against c-kit and platelet-derived growth factor receptor (PDGFR) alpha and beta and EGFR tyrosine kinase.[1]

References

  1. Growth factor receptor expression in orbital lymphangioma: possible therapeutic implications. Esmaeli, B., Prieto, V.G., Gonnering, R., Hawes, M.J., Diba, R., Saadati, H.G., Shepler, T.R., Karcioglu, Z. Orbit (Amsterdam, Netherlands) (2004) [Pubmed]
 
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