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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Syringomyelia with Chiari malformation; 3 unusual cases with implications for pathogenesis.

Syringomyelia is an important cause of neurological deficit. Most cases of non-traumatic syringomyelia occur in association with a Chiari malformation. We present three unusual examples of syringomyelia with such an association. The first case is that of syringomyelia in a young woman with Marfan's syndrome, a spontaneous CSF leak and intractable intracranial hypotension. The second is a woman with long-standing lumbo-peritoneal shunt for pseudotumour cerebri who developed an acquired Chiari malformation. A young woman with a Dandy-Walker cyst that herniated into the upper cervical canal is the third case. These cases provide a basis for discussion of the pathogenesis and management of syringomyelia and the Chiari malformation in such cases.[1]

References

  1. Syringomyelia with Chiari malformation; 3 unusual cases with implications for pathogenesis. Owler, B.K., Halmagyi, G.M., Brennan, J., Besser, M. Acta neurochirurgica. (2004) [Pubmed]
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