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MeSH Review


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Disease relevance of Syringomyelia


High impact information on Syringomyelia


Chemical compound and disease context of Syringomyelia

  • Syringomyelia involved the cervicodorsal cord below C3, with a syrinx-free segment between C1 and C3 and no enlargement of the rostral part of the central canal [11].
  • The syringomyelia disappeared in the segmental area of C2 and was decreased in the segmental areas of C5-T6 [12].
  • In nine of 10 patients with syringomyelia, there was a substantial increase in substance P immunoreactivity in the first, second, third, and fifth laminae below the level of the lesion [13].
  • Severe seizures during propofol induction in a patient with syringomyelia receiving baclofen [14].
  • The autopsy demonstrated a slit-like cavity lined with no ependymal cells on the luminal surface in the lower cervical to midthoracic cord, with circumferentially distributed demyelinative lesions, leading to the pathological diagnosis of secondary syringomyelia [15].

Biological context of Syringomyelia

  • OBJECTIVES: To describe the first use of intravenous (IV) ketamine as the sole agent in a patient-controlled analgesic delivery system (ie PCA) in a patient with cervical syringomyelia [16].

Anatomical context of Syringomyelia


Gene context of Syringomyelia


Analytical, diagnostic and therapeutic context of Syringomyelia


  1. Acute respiratory failure as the first sign of Arnold-Chiari malformation associated with syringomyelia. Alvarez, D., Requena, I., Arias, M., Valdés, L., Pereiro, I., De la Torre, R. Eur. Respir. J. (1995) [Pubmed]
  2. Syringomyelia in association with posterior fossa cysts. Banna, M. AJNR. American journal of neuroradiology. (1988) [Pubmed]
  3. Neuropathic osteoarthropathy: diagnostic dilemmas and differential diagnosis. Jones, E.A., Manaster, B.J., May, D.A., Disler, D.G. Radiographics : a review publication of the Radiological Society of North America, Inc. (2000) [Pubmed]
  4. Paraplegia, syringomyelia tarda and neuropathic arthrosis of the shoulder: a triad. Tully, J.G., Latteri, A. Clin. Orthop. Relat. Res. (1978) [Pubmed]
  5. Surgical treatment of post-traumatic myelopathy associated with syringomyelia. Lee, T.T., Alameda, G.J., Camilo, E., Green, B.A. Spine. (2001) [Pubmed]
  6. Computerized axial tomography in syringomyelia. DiChiro, G., Axelbaum, S.P., Schellinger, D., Twigg, H.L., Ledley, R.S. N. Engl. J. Med. (1975) [Pubmed]
  7. Cerebral potentials evoked by painful, laser stimuli in patients with syringomyelia. Treede, R.D., Lankers, J., Frieling, A., Zangemeister, W.H., Kunze, K., Bromm, B. Brain (1991) [Pubmed]
  8. Dystonia of the legs induced by walking or passive movement of the big toe in a patient with cerebellar ectopia and syringomyelia. Berardelli, A., Thompson, P.D., Day, B.L., Rothwell, J.C., O'Brien, M.D., Marsden, C.D. Neurology (1986) [Pubmed]
  9. Metrizamide ventriculography in syringomyelia. Foster, N.L., Wing, S.D., Bray, P.F. Neurology (1980) [Pubmed]
  10. Multiple sclerosis associated with syringomyelia. Sotgiu, S., Sechi, G., Pugliatti, M., Valenti, P., Rosati, G., Achene, A., Conti, M. J. Neurol. Neurosurg. Psychiatr. (1999) [Pubmed]
  11. Endoscopic third ventriculostomy for treatment of noncommunicating syringomyelia associated with a Chiari I malformation and hydrocephalus: case report and pathophysiological considerations. Métellus, P., Dufour, H., Levrier, O., Grisoli, F. Neurosurgery (2002) [Pubmed]
  12. Syringomyelia associated with Hajdu-Cheney syndrome: case report. Tanimoto, A., Tamaki, N., Nagashima, T., Nakamura, M. Neurosurgery (1996) [Pubmed]
  13. Distribution of substance P in the spinal cord of patients with syringomyelia. Milhorat, T.H., Mu, H.T., LaMotte, C.C., Milhorat, A.T. J. Neurosurg. (1996) [Pubmed]
  14. Severe seizures during propofol induction in a patient with syringomyelia receiving baclofen. Manikandan, S., Sinha, P.K., Neema, P.K., Rathod, R.C. Anesth. Analg. (2005) [Pubmed]
  15. Multiple sclerosis with secondary syringomyelia. An autopsy report. Matsuda, M., Tabata, K., Miki, J., Ishigame, H., Asano, M., Ikeda, S. J. Neurol. Sci. (2001) [Pubmed]
  16. Ketamine patient-controlled analgesia for dysesthetic central pain. Cohen, S.P., DeJesus, M. Spinal Cord (2004) [Pubmed]
  17. Spinal cord size in syringomyelia: change with position on metrizamide myelography. Kan, S., Fox, A.J., Viñuela, F., Debrun, G. Radiology. (1983) [Pubmed]
  18. Syringomyelia associated with intradural extramedullary masses of the spinal canal. Quencer, R.M., el Gammal, T., Cohen, G. AJNR. American journal of neuroradiology. (1986) [Pubmed]
  19. Spinal cord tumor-associated syrinx mimicking abdominal epilepsy: a rare cause of childhood abdominal pain. Drexler, D.L., Grill, B.B., Ashwal, S. J. Pediatr. Gastroenterol. Nutr. (1989) [Pubmed]
  20. The "presyrinx" state: a reversible myelopathic condition that may precede syringomyelia. Fischbein, N.J., Dillon, W.P., Cobbs, C., Weinstein, P.R. AJNR. American journal of neuroradiology. (1999) [Pubmed]
  21. Hindbrain-hernia-related syringomyelia without syringobulbia, complicated by permanent nocturnal central hypoventilation requiring non-invasive ventilation. Bhangoo, R., Sgouros, S., Walsh, A.R., Clarke, J.R. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. (2006) [Pubmed]
  22. A novel fibroblast growth factor receptor 2 mutation in Crouzon syndrome associated with Chiari type I malformation and syringomyelia. Fujisawa, H., Hasegawa, M., Kida, S., Yamashita, J. J. Neurosurg. (2002) [Pubmed]
  23. Growth hormone insensitivity syndrome associated with syringomyelia and type I Chiari malformation. Takagi, J., Otake, K., Takahashi, M., Nakao, N., Hirooka, Y., Sahashi, K., Nogimori, T. Intern. Med. (2003) [Pubmed]
  24. Spinal arachnoid cysts associated with syringomyelia: report of two cases and a review of the literature. Takeuchi, A., Miyamoto, K., Sugiyama, S., Saitou, M., Hosoe, H., Shimizu, K. Journal of spinal disorders & techniques. (2003) [Pubmed]
  25. CSF flow measurement in syringomyelia. Brugières, P., Idy-Peretti, I., Iffenecker, C., Parker, F., Jolivet, O., Hurth, M., Gaston, A., Bittoun, J. AJNR. American journal of neuroradiology. (2000) [Pubmed]
  26. Syringomyelia in a patient with rheumatoid subluxation of the cervical spine. Tumiati, B., Casoli, P. J. Rheumatol. (1991) [Pubmed]
  27. Computed tomography in 75 clinical cases of syringomyelia. Aubin, M.L., Vignaud, J., Jardin, C., Bar, D. AJNR. American journal of neuroradiology. (1981) [Pubmed]
  28. Intramedullary schwannoma of the spinal cord. A case report and review of the literature. Binatli, O., Erşahin, Y., Korkmaz, O., Bayol, U. Journal of neurosurgical sciences. (1999) [Pubmed]
  29. Anaesthesia for caesarean section in a patient with syringomyelia. A case report. Roelofse, J.A., Shipton, E.A., Nell, A.C. S. Afr. Med. J. (1984) [Pubmed]
  30. Syringobulbia: a surgical review. Williams, B. Acta neurochirurgica. (1993) [Pubmed]
  31. Magnetic resonance imaging (MRI) in syringomyelia. Tanghe, H.L. Acta neurochirurgica. (1995) [Pubmed]
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