Disease relevance of Syringomyelia

• Magnetic resonance imaging revealed Arnold-Chiari malformation associated with platybasia, basilar impression, syringomyelia and Klippel-Feil syndrome [1].
• This paper presents three patients with a triad of syringomyelia, midline posterior fossa cysts, and hydrocephalus [2].
• Examples of osteoarthropathy from diverse causes are presented including syringomyelia, spinal cord injury, meningomyelocele, diabetes mellitus, congenital insensitivity to pain, steroid injections, syphilis, leprosy, and others [3].
• Paraplegia, syringomyelia tarda and neuropathic arthrosis of the shoulder: a triad [4].
• INTRODUCTION: Progressive post-traumatic cystic myelopathy (PPCM), or syringomyelia, can occur after spinal cord injury [5].

High impact information on Syringomyelia

• The spines of 18 patients with verified (nine cases) or suspected (nine cases) syringomyelia were studied by ACTA-scanning [6].
• Brief cutaneous heat stimuli generated by a CO2 laser were used to elicit late somatosensory evoked cerebral potentials (SEPc) in 10 patients with syringomyelia [7].
• A 45-year-old man with dystonia of the legs was found to have cerebellar ectopia and syringomyelia [8].
• Metrizamide ventriculography in syringomyelia [9].
• Multiple sclerosis associated with syringomyelia [10].

Chemical compound and disease context of Syringomyelia

• Syringomyelia involved the cervicodorsal cord below C3, with a syrinx-free segment between C1 and C3 and no enlargement of the rostral part of the central canal [11].
• The syringomyelia disappeared in the segmental area of C2 and was decreased in the segmental areas of C5-T6 [12].
• In nine of 10 patients with syringomyelia, there was a substantial increase in substance P immunoreactivity in the first, second, third, and fifth laminae below the level of the lesion [13].
• Severe seizures during propofol induction in a patient with syringomyelia receiving baclofen [14].
• The autopsy demonstrated a slit-like cavity lined with no ependymal cells on the luminal surface in the lower cervical to midthoracic cord, with circumferentially distributed demyelinative lesions, leading to the pathological diagnosis of secondary syringomyelia [15].

Biological context of Syringomyelia

• OBJECTIVES: To describe the first use of intravenous (IV) ketamine as the sole agent in a patient-controlled analgesic delivery system (ie PCA) in a patient with cervical syringomyelia [16].

Anatomical context of Syringomyelia

• Spinal cord size in syringomyelia: change with position on metrizamide myelography [17].
• Three cases of syringomyelia associated with intradural extramedullary tumors of the spinal canal are reported to demonstrate their radiographic feature, to postulate a mechanism for their formation, and to describe the clinical deterioration occurring in two patients immediately after metrizamide myelography [18].
• This appears to be a previously undescribed presentation for syringomyelia and emphasizes the importance of considering alternative central nervous system disorders before the diagnosis of abdominal epilepsy is made [19].
• In one patient with severe arachnoid adhesions who initially improved after decompression, late evolution into syringomyelia occurred in association with continued CSF obstruction [20].
• This is usually seen with brain stem lesions and is unexpected when syringomyelia does not extend above C2, in the absence of syringobulbia [21].

Gene context of Syringomyelia

• A novel FGFR2 mutation, Tyr281Cys, was found in familial Crouzon syndrome with Chiari I and syringomyelia [22].
• Growth hormone insensitivity syndrome associated with syringomyelia and type I Chiari malformation [23].
• Syringomyelia existed just caudal to the cyst at T11 [24].
• CSF flow measurement in syringomyelia [25].
• We postulate that this patient's syringomyelia probably represents a complication of cervical rheumatoid arthritis that has not been described [26].

Analytical, diagnostic and therapeutic context of Syringomyelia

• Seventy-five patients with a clinical diagnosis of syringomyelia were examined by computed tomography after intrathecal injection of metrizamide [27].
• Magnetic resonance imaging (MRI) scan disclosed a gadolinium enhanced intramedullary tumor located at C6-T1 associated with syringomyelia [28].
• A 27-year-old White woman with syringomyelia underwent a caesarean section [29].
• Syringobulbia clefts due to a dissection of the CSF under pressure from the fourth ventricle should be differentiated from the ascending syringobulbia which may occur from upward impulsive fluid movements in a syringomyelia [30].
• Based on an own material of 19 patients with syringomyelia and on the related literature a survey is given on the diagnosis, differential diagnosis, postoperative evaluation and the dynamics of CSF and cyst fluids, using magnetic resonance imaging (MRI) [31].

References