Disease relevance of Intracranial Hypotension

• The intracranial hypotension syndrome likely resulted from a CSF leak from one of the meningeal diverticula [1].
• Orthostatic headaches are not always caused by CSF leak or supine intracranial hypotension [2].
• OBJECTIVES: To investigate the role of CSF hypovolemia in spontaneous intracranial hypotension (SIH) syndrome because so-called SIH syndrome sometimes lacks intracranial hypotension [3].
• Spontaneous intracranial hypotension, which may cause Ménière syndrome-like symptoms, is a curable reason of hearing loss, tinnitus, and vertigo. In addition, the fluctuation of the hearing loss with positional changes supports the use of positional audiometry when evaluating hearing loss-related SIH. Venous engorgement in the internal acoustic canal may be related to the symptoms [4].

High impact information on Intracranial Hypotension

• BACKGROUND: Measurement of CSF pressure is the only known way to confirm the diagnosis of intracranial hypotension [5].
• Intracranial hypotension is a cause of diffuse enhancement of the pachymeninx with gadolinium, which often is associated with subdural fluid collections [6].
• Treatment of idiopathic intracranial hypotension: cervicothoracic and lumbar blood patch and peroral steroid treatment [7].
• Atypical clinical presentation of intracranial hypotension: coma [8].
• Epidural blood patch at C2: diagnosis and treatment of spontaneous intracranial hypotension [9].

Chemical compound and disease context of Intracranial Hypotension

• In order to test the hypothesis that intracranial hypotension may have an etiological role in the development of IVH in premature infants, the authors induced intracranial hypotension in the preterm rabbit by the intraperitoneal injection of glycerol [10].
• The authors measured the average diameter of bilateral superior ophthalmic veins (SOV) in 13 patients with spontaneous intracranial hypotension (SIH) on contrast-enhanced, coronal, T1-weighted MRI [11].

Anatomical context of Intracranial Hypotension

• We report a case of spontaneous intracranial hypotension due to a cerebrospinal fluid leak at the C2 level, which was successfully treated by epidural fibrin glue patching [12].

Gene context of Intracranial Hypotension

• Spontaneous intracranial hypotension resulting in coma [13].
• Treatment of spontaneous intracranial hypotension secondary to C-2 meningeal cyst by surgical packing--case report [14].
• Cerebrospinal fluid (CSF) leak at the lumbar puncture (LP) site may induce intracranial hypotension, a common cause of post-LP headache (LPH) [15].

Analytical, diagnostic and therapeutic context of Intracranial Hypotension

• CONCLUSION: Clear CSF images in relation to vertebral bones are obtainable with 3D-CT myelography, rendering this modality very useful for the diagnosis and treatment of spontaneous intracranial hypotension [16].

References