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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Mediastinitis complicating successful mechanical bridge to heart transplantation.

A 22-year-old man with severe end-stage cardiomyopathy required placement of a left ventricular assist device. Purulent mediastinitis and peritonitis developed while the device was in place. The patient survived a prolonged course of treatment, with mediastinal and peritoneal irrigation and parenteral antibiotics, before undergoing a successful heart transplantation 12 weeks after placement of the left ventricular assist device.[1]


  1. Mediastinitis complicating successful mechanical bridge to heart transplantation. Rooks, J.R., Burton, N.A., Lefrak, E.A., Macmanus, Q. J. Heart Lung Transplant. (1992) [Pubmed]
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