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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Xerophthalmia and growth in preschool Indonesian children.

Approximately 4000 preschool children in West Java, Indonesia, were examined for xerophthalmia and weighed and measured at 3-mo intervals from March 1977 to December 1978. Children recovering from xerophthalmia over a 3-mo interval gained an average of 124 g (95% CI 42-206) more over 3 mo than normal children. Their height gain was similar to normal children's. Children who developed xerophthalmia during a 3-mo period gained 199 g (95% CI 114-313) less and grew 0.28 cm (95% CI 0.12, 0.44) less than their normal peers. Children with chronic xerophthalmia gained 120 g (95% CI 49-191) less and grew 0.21 cm (95% CI 0.05-0.37) less than normal children. These data suggest that linear and ponderal growth is adversely affected by chronic and incident xerophthalmia, but that catch-up ponderal growth is experienced by children recovering from xerophthalmia.[1]


  1. Xerophthalmia and growth in preschool Indonesian children. Tarwotjo, I., Katz, J., West, K.P., Tielsch, J.M., Sommer, A. Am. J. Clin. Nutr. (1992) [Pubmed]
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