The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Treatment of palmoplantar psoriasis with intramuscular alefacept.

Alefacept is a dimeric fusion protein that consists of the extracellular CD2- binding portion of human lymphocyte function-associated antigen-3, which is linked to the Fc segment of human IgG1. Alefacept inhibits T-cell activation and proliferation, and induces apoptosis of memory-effector (CD45RO+) T cells in vitro, limiting the inflammatory and uncontrolled keratinocyte proliferation seen in psoriatic lesions. Alefacept is the first biologic approved in the United States for the treatment of moderate to severe chronic plaque psoriasis. This report describes the use of alefacept in 2 patients with extensive and recalcitrant palmoplantar psoriasis who achieved significant improvements on alefacept therapy.[1]

References

  1. Treatment of palmoplantar psoriasis with intramuscular alefacept. Myers, W., Christiansen, L., Gottlieb, A.B. J. Am. Acad. Dermatol. (2005) [Pubmed]
 
WikiGenes - Universities