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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Microtubule motors: LSD2 trips the toggle.

The Perilipin homologue LSD2 has been identified as a regulator of microtubule motor activity in Drosophila embryos. LSD2 is required for the net directional transport of lipid droplets and the new data support a model in which the protein imparts bias onto a molecular toggle that otherwise randomly engages minus and plus end motors in a paired set.[1]


  1. Microtubule motors: LSD2 trips the toggle. Cohen, R.S. Curr. Biol. (2005) [Pubmed]
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