The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

Ultrasound preexposure improves endothelial cell binding and retention on biomaterial surfaces.

In spite of the extensive studies regarding the effects of ultrasound on biological systems, the influence of low-intensity ultrasound on endothelial cells has rarely been investigated. In this work, the effect of ultrasound in improving the binding between endothelial cells and biomaterial substrates was evaluated. Based on the results, low-intensity ultrasound could change the morphology and matrix secretion of endothelial cells, and such effects persisted when preexposed cells were seeded to another substrate. The cells preexposed to ultrasound were spread further on the substrate. The actin stress fibers of ultrasound-preexposed cells on RGD-modified surfaces were especially intense and well oriented. Ultrasound could probably activate cellular integrins and subsequently allow RGD to bind them. A much firmer adhesion of ultrasound-preexposed endothelial cells to the biomaterial surface coated with the RGD-containing protein was demonstrated. Finally, polyurethane small-diameter vascular grafts seeded with ultrasound-preexposed endothelial cells showed enhanced cell retention on graft surfaces upon flushing.[1]

References

  1. Ultrasound preexposure improves endothelial cell binding and retention on biomaterial surfaces. Hsu, S.H., Huang, T.B., Chuang, S.C., Tsai, I.J., Chen, D.C. Journal of biomedical materials research. Part B, Applied biomaterials. (2006) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities