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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Total synthesis of a diastereomer of the marine natural product clavosolide A.

The first total synthesis of the reported structure of the sponge metabolite clavosolide A is described using a Prins cyclisation to assemble the tetrahydropyran core followed by manipulation of the side-chain, dimerisation and finally glycosidation.[1]

References

  1. Total synthesis of a diastereomer of the marine natural product clavosolide A. Barry, C.S., Bushby, N., Charmant, J.P., Elsworth, J.D., Harding, J.R., Willis, C.L. Chem. Commun. (Camb.) (2005) [Pubmed]
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