- TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. Blonska, M., Shambharkar, P.B., Kobayashi, M., Zhang, D., Sakurai, H., Su, B., Lin, X. J. Biol. Chem. (2005)