The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Beta-lactamase inhibitors: relation between kinetic data and in-vitro synergism studies.

Because of the need for control of beta-lactamase-mediated resistance and the recent development of tazobactam, the author has examined the inhibitors of various beta-lactamases for their effectiveness. On the basis of the kinetic data, tazobactam exhibited the highest affinity to various beta-lactamases. A combination with tazobactam was found to enhance the effectiveness of piperacillin against S. aureus producing penicillinase, E. coli producing TEM-1 or TEM 2 enzymes and class I beta-lactamase-derepressed isolates of E. cloacae, Serratia spp. and C. freundii, however not P. aeruginosa, while there was no marked synergism in beta-lactamase-derepressed clones of K. oxytoca.[1]

References

  1. Beta-lactamase inhibitors: relation between kinetic data and in-vitro synergism studies. Cullmann, W. Zentralbl. Bakteriol. (1991) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities