Chemical Compound Review:
Megalomicin (3R,4S,5R,6R,7R,9R,11R,12R,13S ,14R)-4-[(2R...
Synonyms:
Megalomicina, Megalomicine, Piperacilina, Megalomicinum, Piperacillina, ...
- Adverse reactions to piperacillin in cystic fibrosis. Stead, R.J., Kennedy, H.G., Hodson, M.E., Batten, J.C. Lancet (1984)
- Piperacillin and haemorrhagic cystitis. Joy, V.A. Lancet (1979)
- Azlocillin, mezlocillin, and piperacillin: new broad-spectrum penicillins. Eliopoulos, G.M., Moellering, R.C. Ann. Intern. Med. (1982)
- Ceftazidime compared with piperacillin and tobramycin for the empiric treatment of fever in neutropenic patients with cancer. A multicenter randomized trial. The Intercontinental Antimicrobial Study Group. De Pauw, B.E., Deresinski, S.C., Feld, R., Lane-Allman, E.F., Donnelly, J.P. Ann. Intern. Med. (1994)
- Piperacillin to prevent cholangitis after endoscopic retrograde cholangiopancreatography. A randomized, controlled trial. van den Hazel, S.J., Speelman, P., Dankert, J., Huibregtse, K., Tytgat, G.N., van Leeuwen, D.J. Ann. Intern. Med. (1996)
- Double-blind; placebo-controlled trial of piperacillin prophylaxis in preterm membrane rupture. Lockwood, C.J., Costigan, K., Ghidini, A., Wein, R., Chien, D., Brown, B.L., Alvarez, M., Cetrulo, C.L. Am. J. Obstet. Gynecol. (1993)
- Single or triple dose piperacillin prophylaxis in elective cesarean section. Shah, S., Mazher, Y., John, I.S. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. (1998)
- Antibiotic susceptibility among aerobic gram-negative bacilli in intensive care units in 5 European countries. French and Portuguese ICU Study Groups. Hanberger, H., Garcia-Rodriguez, J.A., Gobernado, M., Goossens, H., Nilsson, L.E., Struelens, M.J. JAMA (1999)
- Filgrastim in patients with chemotherapy-induced febrile neutropenia. A double-blind, placebo-controlled trial. Maher, D.W., Lieschke, G.J., Green, M., Bishop, J., Stuart-Harris, R., Wolf, M., Sheridan, W.P., Kefford, R.F., Cebon, J., Olver, I., McKendrick, J., Toner, G., Bradstock, K., Lieschke, M., Cruickshank, S., Tomita, D.K., Hoffman, E.W., Fox, R.M., Morstyn, G. Ann. Intern. Med. (1994)
- Beta-lactam antibiotic therapy in febrile granulocytopenic patients. A randomized trial comparing cefoperazone plus piperacillin, ceftazidime plus piperacillin, and imipenem alone. Winston, D.J., Ho, W.G., Bruckner, D.A., Champlin, R.E. Ann. Intern. Med. (1991)
- Cecropin B enhances betalactams activities in experimental rat models of gram-negative septic shock. Ghiselli, R., Giacometti, A., Cirioni, O., Mocchegiani, F., Orlando, F., D'Amato, G., Sisti, V., Scalise, G., Saba, V. Ann. Surg. (2004)
- Moxalactam plus piperacillin versus moxalactam plus amikacin in febrile granulocytopenic patients. Winston, D.J., Barnes, R.C., Ho, W.G., Young, L.S., Champlin, R.E., Gale, R.P. Am. J. Med. (1984)
- Comparative trial of ticarcillin plus clavulanic acid and piperacillin in the treatment of acute bacterial infection. Pierce, M.A., Wofford, J.D., Cobbs, C.G. Am. J. Med. (1985)
- Biosynthesis of the anti-parasitic agent megalomicin: transformation of erythromycin to megalomicin in Saccharopolyspora erythraea. Volchegursky, Y., Hu, Z., Katz, L., McDaniel, R. Mol. Microbiol. (2000)
- Intra-Golgi transport inhibition by megalomicin. Bonay, P., Munro, S., Fresno, M., Alarcón, B. J. Biol. Chem. (1996)
- A controlled study of ticarcillin plus clavulanic acid versus piperacillin as empiric therapy for fever in the immunocompromised host. Williams, M.E., Harman, C., Scheld, M., Hess, C.E., Donowitz, G.R. Am. J. Med. (1985)
- A prospective evaluation of optimal sampling theory in the determination of the steady-state pharmacokinetics of piperacillin in febrile neutropenic cancer patients. Drusano, G.L., Forrest, A., Plaisance, K.I., Wade, J.C. Clin. Pharmacol. Ther. (1989)
- Piperacillin kinetics. Batra, V.K., Morrison, J.A., Lasseter, K.C., Joy, V.A. Clin. Pharmacol. Ther. (1979)
- Sepsis associated with urinary tract infection. Antibiotic treatment with piperacillin. Tunn, U.W., Thieme, H. Arch. Intern. Med. (1982)
- Megalomicin disrupts lysosomal functions. Bonay, P., Fresno, M., Alarcón, B. J. Cell. Sci. (1997)
- Basophil histamine release remains unaffected by clinical desensitization to penicillin. Pienkowski, M.M., Kazmier, W.J., Adkinson, N.F. J. Allergy Clin. Immunol. (1988)
- Penetration of piperacillin into bronchial mucosa and sputum. Marlin, G.E., Burgess, K.R., Burgoyne, J., Funnell, G.R., Guinness, M.D. Thorax (1981)
- Piperacillin distribution into bile, gallbladder wall, abdominal skeletal muscle, and adipose tissue in surgical patients. Russo, J., Thompson, M.I., Russo, M.E., Saxon, B.A., Matsen, J.M., Moody, F.G., Rikkers, L.F. Antimicrob. Agents Chemother. (1982)
- Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites. Pogliano, J., Pogliano, K., Weiss, D.S., Losick, R., Beckwith, J. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Comparison of intravenous/oral ciprofloxacin plus metronidazole versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections. Cohn, S.M., Lipsett, P.A., Buchman, T.G., Cheadle, W.G., Milsom, J.W., O'Marro, S., Yellin, A.E., Jungerwirth, S., Rochefort, E.V., Haverstock, D.C., Kowalsky, S.F. Ann. Surg. (2000)
- Potential of imipenem as single-agent empiric antibiotic therapy of febrile neutropenic patients with cancer. Wade, J.C., Standiford, H.C., Drusano, G.L., Johnson, D.E., Moody, M.R., Bustamante, C.I., Joshi, J.H., deJongh, C., Schimpff, S.C. Am. J. Med. (1985)
- Simulation of human serum pharmacokinetics of cefazolin, piperacillin, and BRL 42715 in rats and efficacy against experimental intraperitoneal infections. Woodnutt, G., Berry, V., Mizen, L. Antimicrob. Agents Chemother. (1992)
- Susceptibility of Escherichia coli isolates with TEM-1 beta-lactamase to combinations of BRL42715, tazobactam or clavulanate with piperacillin or amoxycillin . Livermore, D.M., Seetulsingh, P. J. Antimicrob. Chemother. (1991)
- Behaviour of beta-lactamase-positive and -negative Staphylococcus aureus isolates in susceptibility tests with piperacillin/tazobactam and other beta-lactam/beta-lactamase inhibitor combinations. Bonfiglio, G., Livermore, D.M. J. Antimicrob. Chemother. (1993)
- Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam. Kuck, N.A., Jacobus, N.V., Petersen, P.J., Weiss, W.J., Testa, R.T. Antimicrob. Agents Chemother. (1989)
- Penicillin-binding proteins 2b and 2x of Streptococcus pneumoniae are primary resistance determinants for different classes of beta-lactam antibiotics. Grebe, T., Hakenbeck, R. Antimicrob. Agents Chemother. (1996)
- Single-dose pharmacokinetics of piperacillin and tazobactam in patients with renal disease. Johnson, C.A., Halstenson, C.E., Kelloway, J.S., Shapiro, B.E., Zimmerman, S.W., Tonelli, A., Faulkner, R., Dutta, A., Haynes, J., Greene, D.S. Clin. Pharmacol. Ther. (1992)