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Chappel, M.C. et al.

Chappel, Ferrario,

ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7).

The discovery of angiotensin-converting enzyme 2 (ACE-2) has revealed a far more complex enzymatic cascade that may influence the renin-angiotensin system within the kidney, specifically the expression of the functional products angiotensin II (Ang II) and Ang-(1-7). The regulation of this critical system involved in blood pressure control must now encompass the integral relationship of ACE and ACE-2 activities.[1]

References

ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7). Chappel, M.C., Ferrario, C.M. Kidney Int. (2006) [Pubmed]

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