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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis.

Ambruticins are a family of polyketides. The antifungal activity of an ambruticin, KOSN-2079, was tested in the mouse model of invasive aspergillosis. KOSN-2079 significantly reduced pulmonary fungal burdens and improved survival over that with the vehicle control. These results support the continued development of ambruticins as antifungal agents.[1]

References

  1. Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis. Chiang, L.Y., Ejzykowicz, D.E., Tian, Z.Q., Katz, L., Filler, S.G. Antimicrob. Agents Chemother. (2006) [Pubmed]
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