A WNK in the kidney controls blood pressure.
Precise control of sodium excretion by the kidney is critical for maintaining fluid and electrolyte homeostasis. A new mouse model provides compelling evidence that a kinase, WNK4, provides key signals for regulating blood pressure and potassium balance by controlling the structure and function of the distal convoluted tubule.[1]References
- A WNK in the kidney controls blood pressure. Coffman, T.M. Nat. Genet. (2006) [Pubmed]
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