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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Nuclear matrix protein mitotin messenger RNA is expressed at constant levels during the cell cycle.

During the course of an investigation on nuclear matrix protein cDNAs, we have isolated a cDNA clone hybridizing with the messenger RNA encoding mitotin. Mitotin is a 125 kDa/pI 6.5 nuclear matrix protein present in proliferating but not in resting cells. This protein was shown to have a marked increase and characteristic redistribution in G2/M phase of the cell cycle. In this report, using synchronized Raji and WISH cells, we demonstrate that mitotin messenger RNA is expressed at the same level throughout the cell cycle.[1]

References

  1. Nuclear matrix protein mitotin messenger RNA is expressed at constant levels during the cell cycle. Todorov, I.T., Lavigne, J., Sakr, F., Kaneva, R., Foisy, S., Bibor-Hardy, V. Biochem. Biophys. Res. Commun. (1991) [Pubmed]
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