Gene Review:
MCM2 - minichromosome maintenance complex...
Homo sapiens
Synonyms:
BM28, CCNL1, CDCL1, D3S3194, DNA replication licensing factor MCM2, ...
- Stem cell markers: ABCG2 and MCM2 expression in retinoblastoma. Mohan, A., Kandalam, M., Ramkumar, H.L., Gopal, L., Krishnakumar, S. The British journal of ophthalmology. (2006)
- Expression of minichromosome maintenance-2 in human malignant fibrous histiocytomas: Correlations with Ki-67 and P53 expression, and apoptosis. Osaki, M., Osaki, M., Yamashita, H., Shomori, K., Yoshida, H., Ito, H. Int. J. Mol. Med. (2002)
- MCM2--a promising marker for premalignant lesions of the lung: a cohort study. Tan, D.F., Huberman, J.A., Hyland, A., Loewen, G.M., Brooks, J.S., Beck, A.F., Todorov, I.T., Bepler, G. BMC Cancer (2001)
- Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool. Davies, R.J., Freeman, A., Morris, L.S., Bingham, S., Dilworth, S., Scott, I., Laskey, R.A., Miller, R., Coleman, N. Lancet (2002)
- BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication. Todorov, I.T., Attaran, A., Kearsey, S.E. J. Cell Biol. (1995)
- CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein. Cho, W.H., Lee, Y.J., Kong, S.I., Hurwitz, J., Lee, J.K. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Minimally Invasive Follicular Carcinoma Versus Follicular Adenoma: MCM2 Proliferation Marker may be Helpful. Akhtar, M., Scognamiglio, T. Advances in anatomic pathology. (2006)
- Phosphorylation of MCM4 by Cdc7 Kinase Facilitates Its Interaction with Cdc45 on the Chromatin. Masai, H., Taniyama, C., Ogino, K., Matsui, E., Kakusho, N., Matsumoto, S., Kim, J.M., Ishii, A., Tanaka, T., Kobayashi, T., Tamai, K., Ohtani, K., Arai, K. J. Biol. Chem. (2006)
- A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division. Todorov, I.T., Pepperkok, R., Philipova, R.N., Kearsey, S.E., Ansorge, W., Werner, D. J. Cell. Sci. (1994)
- Essential Role of Phosphorylation of MCM2 by Cdc7/Dbf4 in the Initiation of DNA Replication in Mammalian Cells. Tsuji, T., Ficarro, S.B., Jiang, W. Mol. Biol. Cell (2006)
- Expression of minichromosome maintenance 2 (MCM2), Ki-67, and cell-cycle-related molecules, and apoptosis in the normal-dysplasia-carcinoma sequence of the oral mucosa. Kodani, I., Shomori, K., Osaki, M., Kuratate, I., Ryoke, K., Ito, H. Pathobiology (2001)
- Replication competence and senescence in central and peripheral human corneal endothelium. Mimura, T., Joyce, N.C. Invest. Ophthalmol. Vis. Sci. (2006)
- Nuclear matrix protein mitotin messenger RNA is expressed at constant levels during the cell cycle. Todorov, I.T., Lavigne, J., Sakr, F., Kaneva, R., Foisy, S., Bibor-Hardy, V. Biochem. Biophys. Res. Commun. (1991)
- Interleukin-1 alpha upregulates tumor necrosis factor receptors expressed by a human bone marrow stromal cell strain: implications for cytokine redundancy and synergy. Caldwell, J., Emerson, S.G. Blood (1995)
- Expression of the nuclear protein mitotin in differentiating in vitro HL 60 cells. Philipova, R.N., Vassilev, A.P., Kaneva, R.P., Andreeva, P., Todorov, I.T., Hadjiolov, A.A. Biol. Cell (1991)
- A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells. Kumagai, H., Sato, N., Yamada, M., Mahony, D., Seghezzi, W., Lees, E., Arai, K., Masai, H. Mol. Cell. Biol. (1999)
- Identification and characterization of a novel component of the human minichromosome maintenance complex. Sakwe, A.M., Nguyen, T., Athanasopoulos, V., Shire, K., Frappier, L. Mol. Cell. Biol. (2007)
- Cell cycle regulation of chromatin binding and nuclear localization of human Cdc7-ASK kinase complex. Sato, N., Sato, M., Nakayama, M., Saitoh, R., Arai, K., Masai, H. Genes Cells (2003)
- Two immunologically distinct human DNA polymerase alpha-primase subpopulations are involved in cellular DNA replication. Dehde, S., Rohaly, G., Schub, O., Nasheuer, H.P., Bohn, W., Chemnitz, J., Deppert, W., Dornreiter, I. Mol. Cell. Biol. (2001)