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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Morphological study of the capsular organization around tissue expanders coated with N-carboxybutyl chitosan.

Expanders coated with N-carboxybutyl chitosan were inserted into surgical wounds in the dorsal skin of rabbits and the formation of capsular tissue was studied by scanning electron microscopy and transmission electron microscopy. N-carboxybutyl chitosan, in the course of the capsular organization, favours and potentiates the correct proliferation and organization of the tissue, rather than sustaining reactive processes leading to scar formation. N-carboxybutyl chitosan stimulates physiologically the tissue repair process and favours angiogenesis, whilst depressing fibrogenesis to a certain extent. Applications are envisaged in the treatment of wounds and in plastic surgery.[1]

References

  1. Morphological study of the capsular organization around tissue expanders coated with N-carboxybutyl chitosan. Biagini, G., Pugnaloni, A., Damadei, A., Bertani, A., Belligolli, A., Bicchiega, V., Muzzarelli, R. Biomaterials (1991) [Pubmed]
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