Navigator-gated MR angiography of the renal arteries: a potential screening tool for renal artery stenosis.
OBJECTIVE: The purpose of our study was to determine how well unenhanced navigator-gated steady-state free precession (Nav SSFP) MR angiography (MRA) performs as a screening test for the detection of renal artery stenosis. SUBJECTS AND METHODS: Forty patients referred to rule out renal artery stenosis were imaged using an optimized Nav SSFP MRA sequence before conventional contrast-enhanced MRA (CE-MRA). Two radiologists evaluated Nav SSFP for maximum stenosis measurement, and comparison was made with CE-MRA results. RESULTS: Fifteen of the 40 patients had greater than 50% renal artery stenosis as determined on CE-MRA. Sensitivity for detecting renal artery stenosis with Nav SSFP was 100%; specificity, 84%; negative predictive value, 100%; and positive predictive value, 79%. The average mean stenosis difference between Nav SSFP and CE-MRA was 10% +/- 9%. CONCLUSION: Sensitivity and negative predictive value for the detection of renal artery stenosis using Nav SSFP were perfect, with an acceptable specificity of 84%. This suggests Nav SSFP is a promising technique for simple unenhanced screening for the detection of renal artery stenosis.[1]References
- Navigator-gated MR angiography of the renal arteries: a potential screening tool for renal artery stenosis. Maki, J.H., Wilson, G.J., Eubank, W.B., Glickerman, D.J., Millan, J.A., Hoogeveen, R.M. AJR. Am. J. Roentgenol (2007) [Pubmed]
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