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On kynureninase activity.

1) In Mg-deficient rats, kynureninase activity is decreased. 2) p-Hydroxyphenylpyruvate inhibits kynureninase activity. 3) -SH groups in the apoenzyme of kynureninase play a very important role in the enzymatic reaction. 4) 3-Hydroxykynurenine may be a very important regulative metabolite in the 3-hydroxykynurenine----xanthurenic acid pathway.[1]


  1. On kynureninase activity. Shibata, Y., Takeuchi, F., Tsubouchi, R., Haneda, M., Ohta, T., Nakatsuka, M., Nisimoto, Y., Tamai, T., Nomura, S., Fujimoto, H. Adv. Exp. Med. Biol. (1991) [Pubmed]
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