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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Glucose: a novel regulator of notch signaling.

Notch signaling regulates cell fate during the development of many tissues. A new Drosophila mutant, rumi, is defective in Notch signaling because it cannot add glucose to serine in epidermal growth factor repeats of Notch extracellular domain. This is the first biological role for glucose covalently attached to a cell surface signaling receptor.[1]

References

  1. Glucose: a novel regulator of notch signaling. Stanley, P. ACS Chem. Biol. (2008) [Pubmed]
 
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