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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Negative effect on early post-implantation pregnancy and progesterone levels in mice infected with the intestinal trematode Echinostoma caproni.

Infection in mice (BALB/cABom) with the intestinal trematode Echinostoma caproni had a negative influence on pregnancy. The effect of the infection set in immediately following implantation (day 5 of pregnancy) resulting in fewer foetuses being present in infected mice on day 9 than in the controls. Ovulation, fertilization of eggs, and implantation itself were obviously not impaired. The infected mice had significantly lower serum progesterone levels on day 5 of pregnancy than the non-infected controls. It is speculated that the progesterone levels in the infected female mice were too low to secure early post-implantation gestation.[1]


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