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Exercise and other indirect challenges to demonstrate asthma or exercise-induced bronchoconstriction in athletes.

The prevalence of exercise-induced bronchoconstriction is reported to be high among recreational and elite athletes, yet diagnosis is often symptom-based. Indirect challenges such as the laboratory exercise challenge provide objective criteria for proper diagnosis and treatment. However, a standardized protocol using appropriate exercise intensity, duration, and dry air inhalation is often not implemented, and thus a false-negative test may result. This article reviews and describes the symptom-based diagnosis, the exercise challenge, and other indirect challenges such as eucapnic voluntary hyperpnea, hypertonic saline inhalation, and inhaled powdered mannitol as methods to diagnose and evaluate exercise-induced bronchoconstriction. Advantages and disadvantages of each diagnostic procedure are presented.[1]

References

  1. Exercise and other indirect challenges to demonstrate asthma or exercise-induced bronchoconstriction in athletes. Rundell, K.W., Slee, J.B. J. Allergy Clin. Immunol. (2008) [Pubmed]
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