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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Adverse reaction to pomegranate ingestion.

We present a non-atopic 85-year-old woman, with a late-onset recidivant tongue angio-edema due to pomegranate intake, as proven by a double blind oral challenge test. This is the first case ever reported about adverse reaction to pomegranate. We have been unable to demonstrate an IgE-mediated mechanism (prick test, histamine release test and RAST with pomegranate were all negative). We emphasize the importance of clinical history and oral challenge test in the diagnosis of food allergy.[1]

References

  1. Adverse reaction to pomegranate ingestion. Igea, J.M., Cuesta, J., Cuevas, M., Elias, L.M., Marcos, C., Lazaro, M., Compaired, J.A. Allergy (1991) [Pubmed]
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