Fructose transport by Escherichia coli.
The utilization of fructose by Escherichia coli involves, as first step, the uptake of the sugar, normally via the phosphoenolpyruvate-dependent phosphotransferase system (PTS). This fructose-specific PTS differs in several ways from that effecting the uptake of other sugars that also possess the 3,4,5-D-arabino-hexose configuration: these differences are discussed. Mutants that lack the genes ptsI and ptsH, which specify components of the PTS common to most PT-sugars, can mutate further to regain the ability to utilize fructose when this is present in relatively high concentration (i.e. greater than 2 mM) in the medium. Some of the properties of this unusual uptake system is discussed.[1]References
- Fructose transport by Escherichia coli. Kornberg, H.L. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (1990) [Pubmed]
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