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Chemical Compound Review

phosphoenolpyruvate     2-phosphonooxyprop-2-enoic acid

Synonyms: P-enolpyruvate, CHEMBL1235228, CHEBI:44897, HMDB00263, bmse000107, ...
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Disease relevance of phosphoenolpyruvate


High impact information on phosphoenolpyruvate


Biological context of phosphoenolpyruvate


Gene context of phosphoenolpyruvate

  • Three analogs of phosphoenolpyruvic acid: (Z)-phosphoenol-3-fluoropyruvate, (Z)-phosphoenol-3-bromopyruvate and (Z)-phosphoenol-alpha-ketobutyrate were found to be substrates for yeast pyruvate kinase (ATP: pyruvate (Z)-O-phosphotransferase, EC maximal velocities much greater than those found for rabbit muscle pyruvate kinase [8].


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  2. Human erythrocyte pyruvate kinase deficiency: the use of a kinetic study of mutant enzymes for the detection of heterozygotes. Sprengers, E.D., Marie, J., Kahn, A., Punt, K., Staal, G.E. Hum. Genet. (1978) [Pubmed]
  3. Physiological characterisation of a pyruvate-carboxylase-negative Saccharomyces cerevisiae mutant in batch and chemostat cultures. de Jong-Gubbels, P., Bauer, J., Niederberger, P., Stückrath, I., Kötter, P., van Dijken, J.P., Pronk, J.T. Antonie Van Leeuwenhoek (1998) [Pubmed]
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  5. The crystal and molecular structure of phosphoenolpyruvic acid. Weichsel, A., Lis, T., Ruczek, M. Carbohydr. Res. (1989) [Pubmed]
  6. Modulation of proton pumping efficiency in bacterial ATP synthases. Turina, P., Rebecchi, A., D'Alessandro, M., Anefors, S., Melandri, B.A. Biochim. Biophys. Acta (2006) [Pubmed]
  7. Metabolic flux analysis of Candida tropicalis growing on xylose in an oxygen-limited chemostat. Granström, T., Aristidou, A.A., Leisola, M. Metab. Eng. (2002) [Pubmed]
  8. Chemical specificity of pyruvate kinase from yeast. Blumberg, K., Stubbe, J. Biochim. Biophys. Acta (1975) [Pubmed]
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