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Yamahara, J. et al.

Anti-ulcer effect in rats of bitter cardamon constituents.

The effects of bitter cardamon (the fruit of Alpinia oxphylla), used as a medicine and a condiment, on HCl/ethanol-induced gastric lesions in rats were examined. The acetone extract at 50 mg/kg, p.o. significantly inhibited gastric lesions by 57.0%. An analysis of the active constituents in the acetone extract was performed using column chromatography. Nootkatone at 20 mg/kg, p.o. significantly inhibited gastric lesion. These results suggest that nootkatone, the sesquiterpenoid is an important constituent in stomach medications containing bitter cardamon.[1]

References

Anti-ulcer effect in rats of bitter cardamon constituents. Yamahara, J., Li, Y.H., Tamai, Y. Chem. Pharm. Bull. (1990) [Pubmed]

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