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Chemical Compound Review

SureCN309679     4,4a-dimethyl-6-prop-1-en-2- yl-3,4,5,6,7,8...

Synonyms: AC1L2H09, ST50320121, 4674-50-4, 91416-23-8, MCULE-8519555544
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Disease relevance of NOOTKATONE

  • Toxicity and behavioral effects of nootkatone and two of its derivatives, 1,10-dihydronootkatone and tetrahydronootkatone, to Coptotermes formosanus Shiraki were investigated on workers from two different colonies by using topical application assays, repellency assays, and sand barrier assays [1].

High impact information on NOOTKATONE


Biological context of NOOTKATONE


Gene context of NOOTKATONE


Analytical, diagnostic and therapeutic context of NOOTKATONE

  • Four hours after treatment, nootkatone and valencene-13-ol had repellent concentration (RC)50 values of 0.0458 and 0.0712% (wt:vol), respectively; two additional Alaska yellow cedar compounds, nootkatone 1 --> 10 epoxide and carvacrol had reported RC50 values of 0.0858 and 0.112%, respectively [8].


  1. Toxicity and behavioral effects of nootkatone, 1,10-dihydronootkatone, and tetrahydronootkatone to the formosan subterranean termite (Isoptera: Rhinotermitidae). Ibrahim, S.A., Henderson, G., Zhu, B.C., Fei, H., Laine, R.A. J. Econ. Entomol. (2004) [Pubmed]
  2. Inhibition selectivity of grapefruit juice components on human cytochromes P450. Tassaneeyakul, W., Guo, L.Q., Fukuda, K., Ohta, T., Yamazoe, Y. Arch. Biochem. Biophys. (2000) [Pubmed]
  3. Highly efficient production of nootkatone, the grapefruit aroma from valencene, by biotransformation. Furusawa, M., Hashimoto, T., Noma, Y., Asakawa, Y. Chem. Pharm. Bull. (2005) [Pubmed]
  4. Use of nootkatone as a senescence indicator for Rouge La Toma Cv. grapefruit (Citrus paradisi Macf.). Biolatto, A., Sancho, A.M., Cantet, R.J., Güemes, D.R., Pensel, N.A. J. Agric. Food Chem. (2002) [Pubmed]
  5. Nootkatone is a repellent for Formosan subterranean termite (Coptotermes formosanus). Zhu, B.C., Henderson, G., Chen, F., Maistrello, L., Laine, R.A. J. Chem. Ecol. (2001) [Pubmed]
  6. Insecticidal sesquiterpene from Alpinia oxyphylla against Drosophila melanogaster. Miyazawa, M., Nakamura, Y., Ishikawa, Y. J. Agric. Food Chem. (2000) [Pubmed]
  7. Efficacy of vetiver oil and nootkatone as soil barriers against Formosan subterranean termite (Isoptera: Rhinotermitidae). Maistrello, L., Henderson, G., Laine, R.A. J. Econ. Entomol. (2001) [Pubmed]
  8. Repellent activity of fractioned compounds from Chamaecyparis nootkatensis essential oil against nymphal Ixodes scapularis (Acari: Ixodidae). Dietrich, G., Dolan, M.C., Peralta-Cruz, J., Schmidt, J., Piesman, J., Eisen, R.J., Karchesy, J.J. J. Med. Entomol. (2006) [Pubmed]
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