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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Thromboplastin activity of blood monocytes after total hip replacement.

Thromboplastin activity of monocytes from blood of seven patients with total hip replacement was investigated. At 24 h and 48 h after surgery, thromboplastin activity was significantly increased compared to the activity before surgery. Thromboplastin activity of endotoxin-stimulated monocytes was significantly increased at 24 h after surgery. There were no significant changes in Factor V after surgery, Factor VII was significantly lowered at 24 h after surgery, while Factor VIII and fibrinogen were significantly increased at 72 h after surgery. The results indicate that monocyte thromboplastin may be a thrombogenic factor after total hip replacement surgery.[1]


  1. Thromboplastin activity of blood monocytes after total hip replacement. Nygaard, O.P., Unneberg, K., Reikerås, O., Osterud, B. Scand. J. Clin. Lab. Invest. (1990) [Pubmed]
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