The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Central role for the Escherichia coli minC gene product in two different cell division-inhibition systems.

In Escherichia coli, selection of the proper division site at midcell requires the specific inhibition of septation at two other potential division sites, located at each of the cell poles. This site-specific inhibition of septation is mediated by the gene products of the minicell locus (the minB operon) that includes three genes, minC, minD, and minE. In this paper we show that one of the components of this division-inhibition system, the minC gene product, is also an essential component of another division-inhibition system, which is induced by derepression of the dicB gene and leads to inhibition of septation at all potential division sites. The two minC-dependent division-inhibition systems could be functionally distinguished by their different responses to the minE gene product. The results suggest a model in which a common mechanism, mediated by MinC, is responsible for the division block in a class of division-inhibition systems that can be independently activated by different proteins that determine the specific properties of these systems.[1]

References

  1. Central role for the Escherichia coli minC gene product in two different cell division-inhibition systems. de Boer, P.A., Crossley, R.E., Rothfield, L.I. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
 
WikiGenes - Universities