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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Electroconvulsive therapy for iatrogenic hypothalamic-hypopituitarism (CRF-ACTH type).

A 41-year-old man with hypothalamic hypopituitarism (CRF-ACTH type) that persisted for 2 years after discontinuation of exogenous dexamethasone was treated with bilateral ECT for severe chronic depression. The depression improved only evanescently after 17 ECT sessions but the hypothalamic-pituitary suppression cleared completely and permanently, based on responses to four metyrapone stress tests in a 2-year follow-up period. ECT may be an effective treatment for persistent hypothalamic-pituitary suppression, even in the absence of a psychiatric disorder.[1]

References

  1. Electroconvulsive therapy for iatrogenic hypothalamic-hypopituitarism (CRF-ACTH type). Pitts, F.N., Patterson, C.W. The American journal of psychiatry. (1979) [Pubmed]
 
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