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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

The effects of burimamide and metiamide on basal gastric function in the cat.

1 Burimamide injected intravenously in the anaesthetized or conscious cat produced significant increases in gastric acid secretion: in the anaesthetized cat it produced increased gastric mucosal blood flow. 2 Metiamide, in doses which inhibited pentagastrin-stimulated acid secretion, produced no increase in gastric acid secretion in conscious animals, or gastric acid secretion or gastric mucosal blood flow in the anaesthetized cat. 3 Metiamide did not influence the amount of acid which diffused out of the stomach when instilled at pH values between 1.5 and 6. 0. 4 The possible mode of action of burimamide in increasing basal gastric secretion is discussed.[1]

References

  1. The effects of burimamide and metiamide on basal gastric function in the cat. Harris, D.W., Smy, J.R., Reed, J.D., Venables, C.W. Br. J. Pharmacol. (1975) [Pubmed]
 
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