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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Failure of secondary prophylaxis with erythromycin in rheumatic heart disease.

BACKGROUND: Erythromycin is recommended for secondary prophylaxis in children with rheumatic heart disease, who are allergic to penicillin. CASE CHARACTERISTICS: A 9-year-old girl, with rheumatic heart disease, on secondary prophylaxis with erythromycin 250 mg BD, presented with acute rheumatic fever. OUTCOME: Responded to steroids and started on a higher dose (250 mg TDS) of erythromycin for secondary prophylaxis. MESSAGE: There is need to document the resistance of group A streptococci to erythromycin.[1]

References

  1. Failure of secondary prophylaxis with erythromycin in rheumatic heart disease. Yadav, D.K., Anand, P., Bhutia, E. Indian. Pediatr (2013) [Pubmed]
 
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