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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Spontaneous excretion of D-alanine in urine in mutant mice lacking D-amino-acid oxidase.

Urine from mutant mice lacking D-amino-acid oxidase contained a large amount of alanine compared with that from normal mice. Urinary alanine of the mutant mice was sensitive to D-amino-acid oxidase. H.p.l.c. showed that about 94% of the urinary alanine had the D-configuration. These results suggest that D-amino-acid oxidase functions to decompose D-amino acid(s) in normal mice.[1]

References

  1. Spontaneous excretion of D-alanine in urine in mutant mice lacking D-amino-acid oxidase. Konno, R., Nagata, Y., Niwa, A., Yasumura, Y. Biochem. J. (1989) [Pubmed]
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