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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum.

Two histidine-rich protein genes in Plasmodium falciparum are related by an ancestral duplication and interchromosomal transposition. We have followed the inheritance of these genes in a cross between two clones of P. falciparum. Examination of progeny shows that one gene, encoding the protein HRP-II, behaves as expected and may be inherited from either parent. The other gene, encoding HRP-III, has been found to derive from one parent in all progeny examined. We conclude the linkage group marked by HRP-III is favored strongly in the cross. This linkage group spans a region at one end of chromosome 13. Growth studies suggest the favored inheritance is explained by rapid expansion of progeny possessing the HRP-III marker relative to slower growth of progeny without it.[1]

References

  1. A histidine-rich protein gene marks a linkage group favored strongly in a genetic cross of Plasmodium falciparum. Wellems, T.E., Walliker, D., Smith, C.L., do Rosario, V.E., Maloy, W.L., Howard, R.J., Carter, R., McCutchan, T.F. Cell (1987) [Pubmed]
 
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