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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Reversal of tropicamide-induced mydriasis by thymoxamine eye drops.

In a study in 12 healthy volunteers, local instillation of thymoxamine eye drops (0.5%), completely reversed the mydriasis produced by tropicamide (0.5%), but only incompletely that by tropicamide (1.0%). The difference between these effects was statistically significant (p less than 0.025). The thymoxamine eye drops were well tolerated.[1]


  1. Reversal of tropicamide-induced mydriasis by thymoxamine eye drops. McKinna, H., Stewart-Jones, J.H., Edgar, D.F., Turner, P. Current medical research and opinion. (1988) [Pubmed]
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