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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice.

Neutralizing and nonneutralizing monoclonal antibodies to the peplomer glycoprotein and nucleocapsid protein of a mouse hepatitis virus (MHV), MHV-NuU, protected mice against lethal MHV-2 challenge. Histopathologically, livers of mice receiving protective antibodies showed some focal necrotic lesions with remarkable cellular infiltration instead of fulminant hepatitis caused by MHV-2.[1]

References

  1. Protective effect of monoclonal antibodies on lethal mouse hepatitis virus infection in mice. Nakanaga, K., Yamanouchi, K., Fujiwara, K. J. Virol. (1986) [Pubmed]
 
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