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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans.

After ingestion of 400 mg of mescaline sulfate by human volunteers, 3,4,5-trimethoxybenzoic acid was isolated from urine and identified by gas chromatography-mass spectrometry. The amount of this anionic mescaline metabolite was found to be very low as compared with that of the well-konwn 3,4,5-trimethoxyphenylacetic acid. The significance of this finding is discussed.[1]


  1. 3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans. Demisch, L., Kaczmarczyk, P., Seiler, N. Drug Metab. Dispos. (1978) [Pubmed]
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