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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

The behavioral actions of diazepam and oxazepam are similar.

In a double-blind and randomized study, we assessed the comparative pharmacodynamic profiles and behavioral effects of diazepam and oxazepam administered to young healthy volunteers. Diazepam 0.3 mg/kg or oxazepam 1.2 mg/kg or placebo were each administered orally to 13 subjects who were tested with tasks which measured learning and memory, cognition, psychomotor performance and mood before and for 9 h after treatment. The two drugs had similar actions, although subjective effects were milder after oxazepam, which also had a slower onset of action. There was no evidence of rebound behavioral impairment.[1]

References

  1. The behavioral actions of diazepam and oxazepam are similar. Mewaldt, S.P., Ghoneim, M.M., Hinrichs, J.V. Psychopharmacology (Berl.) (1986) [Pubmed]
 
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