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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Comparative activity of cefotetan against plasmid-encoded aminoglycoside-resistant enterobacteria strains.

304 strains of R-plasmid harbouring enterobacteria resistant to aminoglycosides were studied for their susceptibilities to a range of antibiotics, including cefotetan. Cefotetan and latamoxef were the most active of the four cephamycins tested and all were stable to the beta-lactamases produced by these strains. No new beta-lactamases (SHV-2, CTX-1, TEM-4, CAZ-1) were found in these strains capable of hydrolysing third generation cephalosporins. The activity of cefotetan against these multi-resistant, beta-lactamase producing strains may be of clinical value.[1]

References

  1. Comparative activity of cefotetan against plasmid-encoded aminoglycoside-resistant enterobacteria strains. Gomez-Lus, R., Otal, I., Gomez-Lus, M.L., Sarraseca, C., Castillo, J., Gil, J., Rubio, M.C. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy. (1988) [Pubmed]
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