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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

False positive indium-111 white blood cell scan in a closed clavicle fracture.

Aggressive treatment of the multiply injured patient often requires early fixation of many fractures, some of which may be open. Often, patients develop postoperative fevers requiring a thorough workup to rule out infection. Recently, indium-111 white blood cell (WBC) imaging has become a valuable adjunct in the diagnosis of acute infection. The patient described had a simple, closed clavicle fracture with markedly increased activity on an indium-111 WBC scan obtained for fever workup. This subsequently proved to be a normal, healing, noninfected fracture by other diagnostic techniques. Noninfected, simple closed fractures should be added to the list of causes for a false-positive indium-111 WBC scan.[1]


  1. False positive indium-111 white blood cell scan in a closed clavicle fracture. Friedman, R.J., Gordon, L. Journal of orthopaedic trauma. (1988) [Pubmed]
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