The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Clavicle


Psychiatry related information on Clavicle

  • Most of the men with a fracture of the lateral clavicle are registered at the Department of Alcohol Diseases, making this injury a marker of alcohol abuse [6].

High impact information on Clavicle

  • In Fgf10-/- embryos, limb bud formation was initiated but outgrowth of the limb buds did not occur; however, formation of the clavicles was not affected [7].
  • Cleidocranial dysplasia (CCD) is an autosomal dominant disorder characterized by hypoplastic or absent clavicles, large fontanelles, dental anomalies and delayed skeletal development [8].
  • Cx43-deficient animals also exhibited retarded ossification of the clavicles, ribs, vertebrae, and limbs, demonstrating that skeletal abnormalities are not restricted to a neural crest defect [9].
  • The latency of N20 measured from N9 at the clavicle and the absolute latency of P40 were significantly correlated with the length of MRI abnormalities in the ipsilateral cervical cord [10].
  • The N13 potential, recorded from the low cervical region to a supraglottal reference, was most frequently abnormal in patients with MRI lesions at C6 or C7, whereas P14, recorded from the scalp to a clavicle reference, was most often affected by lesions at Cl or the cervicomedullary junction [10].

Chemical compound and disease context of Clavicle


Biological context of Clavicle


Anatomical context of Clavicle


Associations of Clavicle with chemical compounds

  • The first 99mTc-methylene diphosphonate bone scan showed increased bilateral and symmetric uptake in the ribs, clavicles and iliac bones [20].
  • The results agree with earlier observations that the C4 segment innervates the clavicle and imply that patients with a lesion at or above C4 may have elevated clavicular vibratory thresholds [21].
  • In patients with severe baseline vertebral fractures, raloxifene 60 mg/day decreased the risks of new vertebral [RR 0.74 (95% Cl 0.54, 0.99); P = 0.048] and nonvertebral (clavicle, humerus, wrist, pelvis, hip, and leg) fractures [RH 0.53 (95% CI 0.29, 0.99); P = 0.046] at 3 years [22].
  • We attempted to reconstruct the mandible at the time of tumor resection in a group of patients, using titanium mesh with marrow, rib, scapular spine, and clavicle [23].
  • Patients typically have manageable long-term symptoms without any intervention, but some may require a steroid injection or distal clavicle excision for chronic pain from degenerative changes at the AC joint due to the injury [24].

Gene context of Clavicle

  • Our observations highlight the role of MSX2 in clavicular development and the importance of radiological examination of the clavicles in subjects with PFM [25].
  • The clavicle of Ccd mice showed a smaller band of mesenchymal cell condensation than in wild-type mice [26].
  • 5. In the lateral part of the clavicle type I collagen expression was not detected until E14.5 and osteopontin expression only appeared at E15 [26].
  • The results of this investigation indicate that the fracture of the clavicle is a significant and peculiar factor in stimulating CT secretion [27].
  • Calcitonin and parathyroid hormone in newborn infants with fracture of the clavicle [27].

Analytical, diagnostic and therapeutic context of Clavicle

  • The perimeters of the dissection extend from the midline anteriorly to the anterior border of the trapezius muscle posteriorly, and from the clavicle to the mandible [28].
  • BACKGROUND: This study aims to investigate the effect of irradiation on vestibular evoked myogenic potentials (VEMPs) in nasopharyngeal carcinoma (NPC) survivors, because radiotherapy to NPC covers a column from the basal skull to the clavicle level [29].


  1. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Mundlos, S., Otto, F., Mundlos, C., Mulliken, J.B., Aylsworth, A.S., Albright, S., Lindhout, D., Cole, W.G., Henn, W., Knoll, J.H., Owen, M.J., Mertelsmann, R., Zabel, B.U., Olsen, B.R. Cell (1997) [Pubmed]
  2. Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype. Erlebacher, A., Derynck, R. J. Cell Biol. (1996) [Pubmed]
  3. Further delineation of the Yunis-Varon syndrome. Hennekam, R.C., Vermeulen-Meiners, C. J. Med. Genet. (1989) [Pubmed]
  4. Osteomalacia in a patient with anorexia nervosa. Verbruggen, L.A., Bruyland, M., Shahabpour, M. J. Rheumatol. (1993) [Pubmed]
  5. Comparison of a new pressurized saline canister versus syringe irrigation for laceration cleansing in the emergency department. Chisholm, C.D., Cordell, W.H., Rogers, K., Woods, J.R. Annals of emergency medicine. (1992) [Pubmed]
  6. Shoulder injuries common in alcoholics. An analysis of 413 injuries. Nordqvist, A., Petersson, C.J. Acta orthopaedica Scandinavica. (1996) [Pubmed]
  7. Fgf10 is essential for limb and lung formation. Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato, T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N., Kato, S. Nat. Genet. (1999) [Pubmed]
  8. Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Lee, B., Thirunavukkarasu, K., Zhou, L., Pastore, L., Baldini, A., Hecht, J., Geoffroy, V., Ducy, P., Karsenty, G. Nat. Genet. (1997) [Pubmed]
  9. Connexin43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction. Lecanda, F., Warlow, P.M., Sheikh, S., Furlan, F., Steinberg, T.H., Civitelli, R. J. Cell Biol. (2000) [Pubmed]
  10. Correlation of SEP abnormalities with brain and cervical cord MRI in multiple sclerosis. Turano, G., Jones, S.J., Miller, D.H., Du Boulay, G.H., Kakigi, R., McDonald, W.I. Brain (1991) [Pubmed]
  11. Bleedout efficiency, carcass damage, and rigor mortis development following electrical stunning or carbon dioxide stunning on a shackle line. Kang, I.S., Sams, A.R. Poult. Sci. (1999) [Pubmed]
  12. Osteomyelitis of the clavicle secondary to infected Hickman catheter. Kravitz, A.B. JPEN. Journal of parenteral and enteral nutrition. (1989) [Pubmed]
  13. Cleidocranial dysplasia: clinical and molecular genetics. Mundlos, S. J. Med. Genet. (1999) [Pubmed]
  14. The first-appearance of neutrophils in the human fetal bone marrow cavity. Slayton, W.B., Li, Y., Calhoun, D.A., Juul, S.E., Iturraspe, J., Braylan, R.C., Christensen, R.D. Early Hum. Dev. (1998) [Pubmed]
  15. Linking structural variability in long bone diaphyses to habitual behaviors: foragers from the southern African Later Stone Age and the Andaman Islands. Stock, J., Pfeiffer, S. Am. J. Phys. Anthropol. (2001) [Pubmed]
  16. A transsternal approach to the upper thoracic vertebrae. Sundaresan, N., Shah, J., Feghali, J.G. Am. J. Surg. (1984) [Pubmed]
  17. A false negative technetium 99m bone scan in a 53-year-old man with a fractured tibia and fractured clavicles conducted 88 h after the accident. Hetsroni, I., Shabat, S., Mann, G. Injury. (2004) [Pubmed]
  18. The LifeSite hemodialysis access system: implications for the nephrology nurse. Haynes, B.J., Quarles, A.W., Vavrinchik, J., White, J., Pedan, A. Nephrology nursing journal : journal of the American Nephrology Nurses' Association. (2002) [Pubmed]
  19. Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study. Rubin, J.P., Xie, Z., Davidson, C., Rosow, C.E., Chang, Y., May, J.W. Plast. Reconstr. Surg. (2005) [Pubmed]
  20. Flare response seen in therapy for osteomalacia. Akaki, S., Ida, K., Kanazawa, S., Takeda, Y., Hiraki, Y., Endo, T. J. Nucl. Med. (1998) [Pubmed]
  21. Vibratory perception thresholds at the clavicle in patients with spinal cord injury. Herszkowicz, I., Berić, A., Lindblom, U. J. Neurol. Neurosurg. Psychiatr. (1986) [Pubmed]
  22. Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Delmas, P.D., Genant, H.K., Crans, G.G., Stock, J.L., Wong, M., Siris, E., Adachi, J.D. Bone (2003) [Pubmed]
  23. Experience with immediate and delayed mandibular reconstruction. Lawson, W., Loscalzo, L.J., Baek, S.M., Biller, H.F., Krespi, Y.P. Laryngoscope (1982) [Pubmed]
  24. Decision making: operative versus nonoperative treatment of acromioclavicular joint injuries. Bradley, J.P., Elkousy, H. Clinics in sports medicine. (2003) [Pubmed]
  25. Parietal foramina with cleidocranial dysplasia is caused by mutation in MSX2. Garcia-Miñaur, S., Mavrogiannis, L.A., Rannan-Eliya, S.V., Hendry, M.A., Liston, W.A., Porteous, M.E., Wilkie, A.O. Eur. J. Hum. Genet. (2003) [Pubmed]
  26. Mouse clavicular development: analysis of wild-type and cleidocranial dysplasia mutant mice. Huang, L.F., Fukai, N., Selby, P.B., Olsen, B.R., Mundlos, S. Dev. Dyn. (1997) [Pubmed]
  27. Calcitonin and parathyroid hormone in newborn infants with fracture of the clavicle. Bagnoli, F., Bruchi, S., Sardelli, S., Vispi, L., Buonocore, G., Franchi, F., Bracci, R. Calcif. Tissue Int. (1984) [Pubmed]
  28. Radical neck dissection. Conley, J. Laryngoscope (1975) [Pubmed]
  29. Effect of irradiation on vestibular evoked myogenic potentials in nasopharyngeal carcinoma survivors. Wu, C.C., Young, Y.H., Ko, J.Y. Head & neck. (2003) [Pubmed]
WikiGenes - Universities