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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Glycine and Na+ transport in preimplantation mouse embryos.

The dependence of glycine uptake on glycine and Na+ concentrations was determined and compared in 2-cell embryos and blastocysts. In both, uptake was by a combination of a Na+-independent non-saturable route and a Na+-dependent saturable system with Km values of 62 microM and 274 microM for 2-cell embryos and blastocysts respectively. Na+-dependent saturable uptake by embryos of both stages had a Hill coefficient of 2 for Na+, indicating co-transport of 2 Na+ with each glycine molecule. These results suggest that glycine enters 2-cell embryos by the gly-system, and blastocysts by a similarly Na+-dependent system with characteristics resembling the A-system.[1]

References

  1. Glycine and Na+ transport in preimplantation mouse embryos. Hobbs, J.G., Kaye, P.L. J. Reprod. Fertil. (1986) [Pubmed]
 
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