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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The monomethylethanolamine- and dimethylethanolamine-base exchange reactions of rat-brain microsomal fraction.

The ability of crude rat-brain microsome preparations to convert DME and MME to their corresponding phospholipid was explored. In common with the other base-exchange reactions, the incorporations of DME and MME were stimulated by about 1-4 mM Ca2+, possessed slightly alkaline pH optima, were energy independent and were unaffected by exogenous phospholipids. The Km values were 0.97 mM and 0.5 mM and the Vmax values were 9.6 nmol/mg protein per h and 6.25 nmol/mg protein per h for DME and MME, respectively. The P3 fraction of the brain and heart had the highest specific activities of particles prepared from several tissues.[1]

References

  1. The monomethylethanolamine- and dimethylethanolamine-base exchange reactions of rat-brain microsomal fraction. Kanfer, J.N. Biochim. Biophys. Acta (1986) [Pubmed]
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