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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Concurrent pineoblastoma and unilateral retinoblastoma: a forme fruste of trilateral retinoblastoma?

A 10-month-old boy who presented with strabismus and symptoms of intracranial hypertension was found to have a pineoblastoma and a unilateral ocular retinoblastoma. Despite enucleation of the eye, subtotal removal of the pineoblastoma, and craniospinal axis irradiation, the patient died 6 months later from disseminated intracranial neoplasm. As there was no clinical evidence of bilateral retinoblastoma, this case may represent a forme fruste of the trilateral retinoblastoma complex. The clinicopathological features of this unusual syndrome are reviewed.[1]

References

  1. Concurrent pineoblastoma and unilateral retinoblastoma: a forme fruste of trilateral retinoblastoma? Whittle, I.R., McClellan, K., Martin, F.J., Johnston, I.H. Neurosurgery (1985) [Pubmed]
 
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