The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Pinealoma


High impact information on Pinealoma


Chemical compound and disease context of Pinealoma


Biological context of Pinealoma


Anatomical context of Pinealoma


Gene context of Pinealoma

  • Pineal parenchymal tumor (PPT) differentiation was confirmed by immunohistochemical detection of neuroendocrine markers (synaptophysin, neurofilaments, and chromogranin A) [22].
  • In the remaining tumor, 10% to 14% the positively GFAP antisera-stained cells could be seen in some areas; this tumor was considered a pineocytoma with astrocytic differentiation [23].
  • Suppression of plasma prolactin in a patient with a pinealocytoma [14].
  • Plasma melatonin, LH, FSH, PRL, and corticoids were measured in two patients with pineal tumors [10].
  • The incidence of a positive family history of RB in patients with pinealoma was higher than expected (62% of patients), which may be related to earlier surveillance and treatment of patients with positive family histories of RB [24].

Analytical, diagnostic and therapeutic context of Pinealoma


  1. Midline pineal tumors and suprasellar germinomas: highly curable by irradiation. Sung, D.I., Harisliadis, L., Chang, C.H. Radiology. (1978) [Pubmed]
  2. Gadolinium-enhanced MR angiography. Creasy, J.L., Price, R.R., Presbrey, T., Goins, D., Partain, C.L., Kessler, R.M. Radiology. (1990) [Pubmed]
  3. Concurrent pineoblastoma and unilateral retinoblastoma: a forme fruste of trilateral retinoblastoma? Whittle, I.R., McClellan, K., Martin, F.J., Johnston, I.H. Neurosurgery (1985) [Pubmed]
  4. Calcineurin, a calcium/calmodulin-regulated protein phosphatase, in mammalian neuroendocrine cells and neoplasms. Goto, S., Nagahiro, S., Ushio, Y., Hirano, A. Neurosci. Lett. (1992) [Pubmed]
  5. A hemizygous A to CC base change of the CHM gene causing choroideremia associated with pinealoma. Hotta, Y., Fujiki, K., Hayakawa, M., Kohno, N., Kitagawa, H., Doi, R., Kanai, A. Graefes Arch. Clin. Exp. Ophthalmol. (1997) [Pubmed]
  6. Diagnostic potential of melatonin analysis in pineal tumors. Miles, A., Tidmarsh, S.F., Philbrick, D., Shaw, D.M. N. Engl. J. Med. (1985) [Pubmed]
  7. Modification of hydroxyindole-O-methyltransferase activity in experimental pineocytomas induced in hamsters by a human papovavirus (JC). Quay, W.B., Ma, Y.H., Varakis, J.N., ZuRhein, G.M., Padgett, B.L., Walker, D.L. J. Natl. Cancer Inst. (1977) [Pubmed]
  8. High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas. Gururangan, S., McLaughlin, C., Quinn, J., Rich, J., Reardon, D., Halperin, E.C., Herndon, J., Fuchs, H., George, T., Provenzale, J., Watral, M., McLendon, R.E., Friedman, A., Friedman, H.S., Kurtzberg, J., Vredenbergh, J., Martin, P.L. J. Clin. Oncol. (2003) [Pubmed]
  9. Differential expression of retinal proteins in a pineal parenchymal tumor. Lopes, M.B., Gonzalez-Fernandez, F., Scheithauer, B.W., VandenBerg, S.R. J. Neuropathol. Exp. Neurol. (1993) [Pubmed]
  10. Plasma melatonin, luteinizing hormone, follicle-stimulating hormone, prolactin, and corticoids in two patients with pinealoma. Kennaway, D.J., McCulloch, G., Matthews, C.D., Seamark, R.F. J. Clin. Endocrinol. Metab. (1979) [Pubmed]
  11. Immunohistochemical, ultrastructural, biochemical and in vitro studies of a pineocytoma. Fèvre-Montange, M., Jouvet, A., Privat, K., Korf, H.W., Champier, J., Reboul, A., Aguera, M., Mottolese, C. Acta Neuropathol. (1998) [Pubmed]
  12. Treatment of patients with pineoblastoma with high dose cyclophosphamide. Ashley, D.M., Longee, D., Tien, R., Fuchs, H., Graham, M.L., Kurtzberg, J., Casey, J., Olson, J., Meier, L., Ferrell, L., Kerby, T., Duncan-Brown, M., Stewart, E., Colvin, O.M., Pipas, J.M., McCowage, G., McLendon, R., Bigner, D.D., Friedman, H.S. Med. Pediatr. Oncol. (1996) [Pubmed]
  13. So-called intracranial germ cell tumours: personal experiences and a theory of their pathogenesis. Sano, K., Matsutani, M., Seto, T. Neurol. Res. (1989) [Pubmed]
  14. Suppression of plasma prolactin in a patient with a pinealocytoma. Kraft, K., Edelmann, A., Entzian, W., Nocke-Finck, L. Horm. Metab. Res. (1984) [Pubmed]
  15. A new pineoblastoma cell line, PER-480, with der(10)t(10;17), der(16)t(1;16), and enhanced MYC expression in the absence of gene amplification. Kees, U.R., Spagnolo, D., Hallam, L.A., Ford, J., Ranford, P.R., Baker, D.L., Callen, D.F., Biegel, J.A. Cancer Genet. Cytogenet. (1998) [Pubmed]
  16. The analysis of p53 tumor suppressor gene in pineal parenchymal tumors. Tsumanuma, I., Sato, M., Okazaki, H., Tanaka, R., Washiyama, K., Kawasaki, T., Kumanishi, T. Nōshuyō byōri = Brain tumor pathology. (1995) [Pubmed]
  17. Pineal parenchymal tumours: II. On the aggressive behaviour of pineoblastoma in patients with an inherited mutation of the RB1 gene. Plowman, P.N., Pizer, B., Kingston, J.E. Clinical oncology (Royal College of Radiologists (Great Britain)) (2004) [Pubmed]
  18. Retinoblastoma, pinealoma, and mild overgrowth in a boy with a deletion of RB1 and neighbor genes on chromosome 13q14. Skrypnyk, C., Bartsch, O. Am. J. Med. Genet. A (2004) [Pubmed]
  19. Demonstration of hydroxyindole-O-methyltransferase (HIOMT) mRNA expression in pineal parenchymal tumors: histochemical in situ hybridization. Tsumanuma, I., Tanaka, R., Ichikawa, T., Washiyama, K., Kumanishi, T. J. Pineal Res. (2000) [Pubmed]
  20. Successful combination chemotherapy (cisplatin, vinblastine, and bleomycin) with small-dose irradiation in the treatment of pineoblastoma metastasized into spinal cord: case report. Kurisaka, M., Arisawa, M., Moriki, A., Mori, K. Surgical neurology. (1993) [Pubmed]
  21. Pineal tumors and associated lesions: the effect of ethnicity on tumor type and treatment. Knierim, D.S., Yamada, S. Pediatric neurosurgery. (2003) [Pubmed]
  22. Differential somatostatin receptor subtype expression in human normal pineal gland and pineal parenchymal tumors. Champier, J., Jouvet, A., Rey, C., Guyotat, J., Fevre-Montange, M. Cell. Mol. Neurobiol. (2003) [Pubmed]
  23. Immunohistochemical characterization of pineocytomas. Coca, S., Vaquero, J., Escandon, J., Moreno, M., Peralba, J., Rodriguez, J. Clin. Neuropathol. (1992) [Pubmed]
  24. Heritable retinoblastoma and pinealoma. Lueder, G.T., Judisch, G.F., Wen, B.C. Arch. Ophthalmol. (1991) [Pubmed]
  25. S-antigen-like immunoreactivity in a human pineocytoma. Korf, H.W., Klein, D.C., Zigler, J.S., Gery, I., Schachenmayr, W. Acta Neuropathol. (1986) [Pubmed]
  26. Structural and ultrastructural characteristics of human pineal gland, and pineal parenchymal tumors. Jouvet, A., Fèvre-Montange, M., Besançon, R., Derrington, E., Saint-Pierre, G., Belin, M.F., Pialat, J., Lapras, C. Acta Neuropathol. (1994) [Pubmed]
WikiGenes - Universities