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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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The effect of 1 alpha-hydroxyvitamin D2 on calcium metabolism in glucocorticoid-treated rats.

Intestinal calcium transport and renal calcium and phosphate excretion have been measured in normal and prednisolone-treated rats. Prednisolone treatment reduced intestinal calcium transport and increased phosphate excretion, causing a reduction in serum phosphate. Both 1 alpha-hydroxyvitamin D2 and 1 alpha-hydroxyvitamin D3 normalized phosphate excretion, whereas 1 alpha-hydroxyvitamin D3 was not fully effective in serum phosphate. Prednisolone treatment also caused a decreased bone density that was prevented both with 1 alpha-hydroxyvitamin D2 and 1 alpha-hydroxyvitamin D3. 1 alpha-hydroxyvitamin D2 appeared at least as effective as 1 alpha-hydroxyvitamin D3 in correcting the bone disturbance.[1]

References

  1. The effect of 1 alpha-hydroxyvitamin D2 on calcium metabolism in glucocorticoid-treated rats. Sjödén, G.O., Lindgren, J.U., DeLuca, H.F. Bone (1985) [Pubmed]
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