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Chemical Compound Review

Predate     (8R,9R,10S,11S,13S,14S,17R)- 11,17...

Synonyms: Cotolone, Dicortol, Erbacort, Erbasona, Predonine, ...
 
 
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Disease relevance of Predonine

 

Psychiatry related information on Predonine

 

High impact information on Predonine

 

Chemical compound and disease context of Predonine

 

Biological context of Predonine

 

Anatomical context of Predonine

 

Associations of Predonine with other chemical compounds

 

Gene context of Predonine

  • The expression was compared between different types of leukemia and was studied in relation with clinical risk indicators and in vitro cytotoxicity of the MDR-related drugs daunorubicin (DNR), vincristine (VCR), and etoposide (VP16) and the non-MDR-related drugs prednisolone (PRD) and L-asparaginase (ASP) [33].
  • Only prednisolone significantly reduced the expression of TNFalpha, IL-1beta, and IL-6 in the joints [34].
  • Incubation with 2 x 10(-8) M prednisolone down-regulated cell surface CD14 after 72 h, and 2 x 10(-7) M suppressed CD14 expression even after 24 h [35].
  • These results suggest that IL2 and IFN-gamma could enhance colonic epithelial cell injury mediated by the ADCC mechanism in ulcerative colitis and that ADCC enhanced by cytokines is restored by PSL treatment [36].
  • These results show that the overexpression of Delta F beta TrCP1 or beta TrCP1 in vivo induce tumors through beta-catenin activation [37].
  • Calcitonin (10(-10) mol/L) abrogated the stimulating effect of 10 ng/ml RANKL or 10(-9) mol/L prednisolone; similar results were obtained with OPG [38].
 

Analytical, diagnostic and therapeutic context of Predonine

References

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